What happens next depends on the state and circumstances. If a will is missing because it was revoked by the decedent, an earlier will may be used or the state’s intestate succession laws may be used to determine how assets in the estate are distributed. In some cases, a photocopy of a will and evidence that the decedent signed the original may be accepted with proof that the original will was destroyed.
If a will can’t be found and no one is sure there even was a will, the state’s intestate succession laws are used by default.